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KMID : 0370020010150000087
Chung-Ang Journal of Pharmacal Sciences
2001 Volume.15 No. 0 p.87 ~ p.91
Synthesis of Aryl Acetic Acid Amides




Abstract
Six Aryl acetic acid amides as potential nonsteroidal analgesic and antiinflammatory compounds were prepared. Cinmetacin and indomethacin were reacted with dicyclohexyl carbodiimide and hydroxysuccinimide to give active ester (4-5), which was treated with amines to yield indomethacin amides (6-11).
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