KMID : 0370020010150000087
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Chung-Ang Journal of Pharmacal Sciences 2001 Volume.15 No. 0 p.87 ~ p.91
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Synthesis of Aryl Acetic Acid Amides
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Abstract
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Six Aryl acetic acid amides as potential nonsteroidal analgesic and antiinflammatory compounds were prepared. Cinmetacin and indomethacin were reacted with dicyclohexyl carbodiimide and hydroxysuccinimide to give active ester (4-5), which was treated with amines to yield indomethacin amides (6-11).
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